Endovascular Thrombectomy for Anterior Circulation Large Vessel Occlusion Stroke: An Evolution of Trials

Author:

Starikova Natalia12,Räty Silja3,Strbian Daniel3,Kaiser Daniel P. O.45,Gerber Johannes C.45,Huo Xiaochuan6,Qiu Zhongming7,Chen Hui-Sheng8,Kaesmacher Johannes9,Pallesen Lars-Peder510,Barlinn Kristian510,Sun Dapeng6,Abdalkader Mohamad11,Nguyen Thanh N.1112,Nagel Simon1314,Miao Zhongrong6,Puetz Volker510

Affiliation:

1. Department of Neurology, University Clinic of Odessa National Medical University, Odessa, Ukraine

2. TeleHealth Consulting Service, Medical Center “Expert Health,” Odessa, Ukraine

3. Department of Neurology, Helsinki University Hospital and University of Helsinki, Finland

4. Institute of Neuroradiology, University Clinics Carl Gustav Carus an der Technischen Universität Dresden, Dresden, Germany

5. Dresden Neurovascular Center, University Clinics Carl Gustav Carus an der Technischen Universität Dresden, Dresden, Germany

6. Interventional Neuroradiology, Beijing Tiantan Hospital, Beijing, China

7. Department of Neurology, The 903rd Hospital of The Chinese People's Liberation Army, Hangzhou, China

8. Department of Neurology, General Hospital of Northern Theatre Command, Shenyang, China

9. Interventional Neuroradiology, Bern University Hospital, University of Bern, Bern, Switzerland

10. Department of Neurology, University Clinics Carl Gustav Carus an der Technischen Universität Dresden, Dresden, Germany

11. Department of Radiology, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts

12. Department of Neurology, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts

13. Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany

14. Department of Neurology, Klinikum Ludwigshafen, Ludwigshafen, Germany

Abstract

AbstractThe last decade's progress in demonstrating the clinical benefit of endovascular thrombectomy (EVT) in patients with large vessel occlusion stroke has transformed the paradigm of care for these patients. This review presents the milestones in implementing EVT as standard of care, demonstrates the current state of evidence, provides guidance for identifying the candidate patient for EVT, and highlights unsolved and controversial issues. Ongoing trials investigate broadening of EVT indications for patients who present with large core infarction, adjunctive intra-arterial thrombolysis, medium vessel occlusion, low NIHSS, and tandem occlusion.

Publisher

Georg Thieme Verlag KG

Subject

Neurology (clinical),Neurology

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