Affiliation:
1. Division of Colorectal Surgery, Department of Surgery, Columbia University Medical Center, New York, New York
Abstract
AbstractApplying the concept of a “natural history” to hereditary colorectal cancer is an interesting exercise because the way the syndromes are approached has changed so drastically. However, the exercise is instructive as it forces us to think in depth about where we are, where we have been, and, most helpfully, about where we may be going. In this article the diagnosis, along with endoscopic and surgical management of hereditary colorectal cancer are discussed in the context of their history and the changes in genomics and technology that have occurred over the last one hundred years.
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