Recent Advances in Cell Electrospining of Natural and Synthetic Nanofibers for Regenerative Medicine

Author:

Zamani Reza1,Aval Sedigheh1,Pilehvar-Soltanahmadi Younes12,Nejati-Koshki Kazem12,Zarghami Nosratollah12

Affiliation:

1. Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran

2. Stem Cell and Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran

Abstract

AbstractThe progression of nanotechnology provides opportunities to manipulate synthetic and natural materials to mimic the natural structure for tissue engineering applications. The electrospinning technique applies electrostatic principle to fabricate electrospun nanofibers. Nanofiber scaffolds are precisely similar to the native extracellular matrix (ECM) and support cell proliferation, adhesion, tendency to preserve their phenotypic shape and directed growth according to the nanofiber direction. This study reviewed both the natural and synthetic type of nanofibers and described the different properties used to trigger certain process in the tissue development. Also, the potential applications of electrospun scaffolds for regenerative medicine were summarized.

Publisher

Georg Thieme Verlag KG

Subject

Drug Discovery,General Medicine

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