Affiliation:
1. Diabetes Centre-Diabetic Foot Clinic, Second Department
of Internal Medicine, Democritus University of Thrace, University Hospital of
Alexandroupolis, Alexandroupolis, Greece
Abstract
AbstractOcular motor mononeuropathies affect cranial nerves III, IV and VI and are more
frequent in diabetes mellitus, with oculomotor nerve involvement being
predominant. This narrative brief review discusses the clinical manifestations,
diagnosis and management of ocular motor mononeuropathies in subjects with
diabetes. Clinical manifestations often include ptosis, diplopia, and
periorbital pain. Pupillary sparing is a characteristic of third nerve palsy.
Differential diagnosis may be challenging due to overlapping symptoms with nerve
palsies of other aetiologies. Treatment includes optimised glycaemic control and
management of vascular risk factors. Neuroprotective agents, mainly alpha-lipoic
acid and botulinum toxin A have been occasionally used, as well. Spontaneous
recovery is seen in many cases.
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