Position Paper of the German Society for Interventional Radiology (DeGIR) on Prostatic Artery Embolization

Author:

Kovács Attila1,Bücker Arno2,Grimm Marc-Oliver3,Habermann Christian R.4,Katoh Marcus5,Massmann Alexander2,Mahnken Andreas H.6,Meyer Bernhard C.7,Moche Michael8,Reimer Peter9,Teichgräber Ulf10,Wacker Frank K.7,

Affiliation:

1. MediClin Robert Janker Clinic, Clinic of Diagnostic and Interventional Radiology and Neuroradiology, Bonn, Germany

2. Saarland University Medical Center, Clinic of Diagnostic and Interventional Radiology, Homburg/Saar, Germany

3. Jena University Hospital, Department of Urology, Jena, Germany

4. Kath. Marienhospital Hamburg, Department of Diagnostic and Interventional Radiology, Hamburg, Germany

5. Helios-Hospital Krefeld, Diagnostic and Interventional Radiology, Krefeld, Germany

6. Marburg University Hospital, Clinic of Diagnostic and Interventional Radiology, Marburg, Germany

7. Hannover Medical School, Department of Diagnostic and Interventional Radiology, Hannover, Germany

8. Helios-Park-Klinikum Leipzig, Department of Interventional Radiology, Leipzig, Germany

9. Städtisches Klinikum Karlsruhe, Academic teaching hospital of the University of Freiburg, Institute of Diagnostic and Interventional Radiology, Karlsruhe, Germany

10. Jena University Hospital, Department of Radiology, Jena, Germany

Abstract

Background In recent years prostate artery embolization (PAE) evolved into a clinically established minimally invasive endovascular treatment option for lower urinary tract symptoms caused by benign prostate syndrome (BPS). Methods In this interdisciplinary position paper, initiated by the steering group for research of the German Society for Interventional Radiology (IR), the method of PAE is presented and discussed in the context of current evidence. Results PAE is a safe IR procedure for the treatment of BPS. In terms of symptom relief, measured with the IPSS (International Prostate Symptom Score), the PAE has comparable effect, similar to the historic gold standard, transurethral resection (TUR) of the prostate. With regard to reducing subvesical obstruction PAE is inferior to TUR, but does not limit subsequent surgery. Based on current evidence, PAE is recommended by the British National Institute for Health and Care Excellence as an alternative therapy. The feasibility under local anaesthesia and the preservation of sexual function are important arguments for patients in favour of interventional therapy. Patient selection and therapy concepts require close interdisciplinary collaboration between urologists and radiologists. Conclusion Effectiveness and safety of PAE for the treatment of BPS are proven. Further randomized trials should focus on long term outcome and help to identify most suitable indications for PAE. Key Points:  Citation Format

Publisher

Georg Thieme Verlag KG

Subject

Radiology Nuclear Medicine and imaging

Reference71 articles.

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2. S2e guideline of the German urologists: Instrumental treatment of benign prostatic hyperplasia;T Bschleipfer;Der Urologe Ausg A,2016

3. Endoscopic enucleation versus open prostatectomy for treating large benign prostatic hyperplasia: a meta-analysis of randomized controlled trials;M Li;PloS one,2015

4. Holmium laser enucleation of the prostate versus open prostatectomy for prostates greater than 100 grams: 5-year follow-up results of a randomised clinical trial;R M Kuntz;Eur Urol,2008

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