Statement of the Obstetrics and Prenatal Medicine Working Group (AGG – Preterm Birth Section) on “Outpatient Management for Pregnant Women with Preterm Premature Rupture of Membranes (PPROM)”

Author:

Kunze Mirjam1,Maul Holger2,Kyvernitakis Ioannis2ORCID,Stelzl Patrick3,Rath Werner4,Berger Richard5

Affiliation:

1. Klinik für Frauenheilkunde, Universitätsklinikum Freiburg, Freiburg, Germany

2. Frauenkliniken, Asklepios Kliniken Barmbek, Wandsbek und Nord-Heidberg, Hamburg, Germany

3. Universitätsklinik für Gynäkologie, Geburtshilfe und Gynäkologische Endokrinologie, Kepler Universitätsklinikum, Johannes Kepler Universität Linz, Linz, Austria

4. Medizinische Fakultät, Gynäkologie und Geburtshilfe, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, Germany

5. Klinik für Gynäkologie und Geburtshilfe, Marienhaus Klinikum St. Elisabeth, Neuwied, Germany

Abstract

AbstractPreterm premature rupture of membranes (PPROM) is one of the leading causes of perinatal morbidity and mortality. After a PPROM, more than 50% of pregnant women are delivered within 7 days. Fetal and maternal risks are primarily due to infection and inflammation, placental abruption, umbilical cord complications and preterm birth.Standard care usually consists of an expectant approach. Management includes the administration of antenatal steroids and antibiotic therapy. Patients with PPROM require close monitoring.The management of pregnant women with PPROM (inpatient vs. outpatient) is still the subject of controversial debate. The international guidelines also do not offer a clear stance. The statement presented here discusses the current state of knowledge.

Publisher

Georg Thieme Verlag KG

Subject

Maternity and Midwifery,Obstetrics and Gynecology

Reference39 articles.

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2. Preterm Premature Rupture of the Membranes in the Twenty-First Century;E Chien;Obstet Gynecol Clin North Am,2020

3. Preterm premature rupture of membranes: a randomized study of home versus hospital management;SJ Carlan;Obstet Gynecol,1993

4. Randomized controlled trial of inpatient vs. outpatient management of PPROM;G Ryan;Am J Obstet Gynecol,1999

5. Planned home versus hospital care for preterm prelabour rupture of the membranes (PPROM) prior to 37 weeksʼ gestation;G Abou El Senoun;Cochrane Database Syst Rev,2014

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