Histology and Long-term Clinical Outcome of Crushed Cartilage with Double-layer Gelatin Sponge Membrane for Dorsum Refinement in Primary Rhinoplasty

Author:

Nocini Riccardo1,Abdulraheem Maryam2,Galzignato Pier-Francesco1,Manzini Jessica3,Bernardi Paolo4,Conti Giamaica4,Sbarbati Andrea4,Chirumbolo Salvatore4ORCID,Bertossi Dario5

Affiliation:

1. Unit of Oral and Maxillofacial Surgery, Department of Surgery, Dentistry, Paediarics and Gynaecology, University of Verona, Verona, Italy

2. Department of Otolaryngology, Ambulatory Care Center (ACC), Hamad Medical Corporation (HMC), Doha, Qatar

3. Azienda Ospedaliera Universitaria Integrata (AOUI) Policlinico GB Rossi, Verona, Italy

4. Unit of Human Anatomy, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy

5. Unit of Otorhinolaryngology, Department of Surgery, Dentistry, Paediarics and Gynaecology, University of Verona, Verona, Italy

Abstract

AbstractThis article demonstrates the ability to use autologous crushed cartilage grafts in rhinoplasty with rapid recovery and optimal nasal functionality without any tissue damage and allows its rapid rejuvenation. Eligible patients underwent primary rhinoplasty using autologous crushed cartilage graft followed by microscopy imaging of the grafted tissue after recovery. Tissue and cytological analysis using optical microscopy, transmission electronic microscopy (TEM), and scanning electronic microscopy (SEM) showed complete viability of chondrocytes, formation of new collagen fibers, neo-perichondrium, neo-angiogenesis, and exhibiting optimal aesthetic outcome. The surgical approach is easy to perform, feasible, and less time-consuming, with excellent tissue rejuvenation and rapid recovery.

Publisher

Georg Thieme Verlag KG

Subject

Surgery

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