Affiliation:
1. College of Pharmaceutical Science, Zhejiang University of Technology
2. College of Chemical Engineering, Zhejiang University of Technology
Abstract
AbstractThe reaction of 5-aminopyrazoles with 1,3-diarylpropenes mediated by 2,3-dichloro-5,6-dicyano-1,4-benzoquinone, with subsequent intramolecular cyclization and dehydroaromatization in the presence of Cu(OTf)2/tert-butyl hydroperoxide, gave a series of pyrazolo[3,4-b]pyridines in moderate to excellent yields. The reaction has the advantages of high atom economy, a wide substrate scope, and a one-pot procedure.
Funder
National Natural Science Foundation of China
Cited by
2 articles.
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