A Case Report of Neisseria sicca Endocarditis in a Patient with Tissue Aortic Valve: Favorable Outcome Following Prompt Multidisciplinary Team Management

Author:

Jamil Husam1,Ezzo Talal2,Doumi Aymen3,Diab Zeinab Abdallah Elias3,Saleem Anum4

Affiliation:

1. Acute Medicine, Yorkshire and Humber Deanery, Leeds, UK

2. Cardiology, Calderdale and Huddersfield Foundation Trust, Halifax, UK

3. Acute Medicine, Yorkshire and Humber Deanery, Hull, UK

4. Microbiology, Calderdale and Huddersfield Foundation Trust, Halifax, UK

Abstract

Neisseria sicca is commonly found in oral flora and is usually deemed harmless. Neisseria sicca is very rarely associated with infective endocarditis and has a high mortality rate with it. We present a case of infective endocarditis in a 57-year-old male who presented with fever, lethargy, and reduced mobility and was admitted to an acute medical unit of a UK district general hospital. Serial blood cultures grew Neisseria sicca and transoesophageal echocardiography confirmed vegetation on the aortic valve. As per microbiology advice, his antibiotic treatment was adjusted to oral ciprofloxacin and intravenous ceftriaxone for 6 weeks given this organism’s sensitivity. The cardiology team arranged outpatient appointments for long-term follow-ups. Involving acute medicine, microbiology, and cardiology teams as part of a multidisciplinary team (MDT) led to good clinical outcomes and patients remained alive and well on follow-ups. So far only 27 cases have been documented and we think our work would increase insights into management strategies for this condition particularly the utilization of the MDT approach.

Publisher

Mark Allen Group

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1. Linezolid;Reactions Weekly;2025-03-22

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