The frequency of joint hemorrhages and procedures in nonsevere hemophilia A vs B

Author:

Soucie J. Michael1,Monahan Paul E.23,Kulkarni Roshni4,Konkle Barbara A.56,Mazepa Marshall A.7

Affiliation:

1. Division of Blood Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA;

2. Department of Pediatrics and

3. Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill, NC;

4. Department of Pediatrics and Human Development, Michigan State University, East Lansing, MI;

5. BloodworksNW, Seattle, WA;

6. Department of Medicine, University of Washington, Seattle, WA; and

7. Department of Medicine, University of Minnesota, Minneapolis, MN

Abstract

Key Points Joint hemorrhages and orthopedic procedures are more frequent in patients with hemophilia A than in those with hemophilia B. FA levels of 20% may be required to prevent all joint hemorrhages.

Publisher

American Society of Hematology

Subject

Hematology

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