Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages

Author:

Emile Jean-François12ORCID,Abla Oussama3,Fraitag Sylvie4,Horne Annacarin5,Haroche Julien67,Donadieu Jean18,Requena-Caballero Luis9,Jordan Michael B.10,Abdel-Wahab Omar11,Allen Carl E.12,Charlotte Frédéric713,Diamond Eli L.14,Egeler R. Maarten3,Fischer Alain1516,Herrera Juana Gil17,Henter Jan-Inge18,Janku Filip19,Merad Miriam20,Picarsic Jennifer21,Rodriguez-Galindo Carlos22,Rollins Barret J.2324,Tazi Abdellatif25,Vassallo Robert26,Weiss Lawrence M.27

Affiliation:

1. Research Unit EA4340, Versailles University, Paris-Saclay University, Boulogne, France;

2. Pathology Department, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Boulogne, France;

3. Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada;

4. Pathology Department, Necker Hospital, Paris, France;

5. Department of Women’s and Children’s Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden;

6. Department of Internal Medicine and French Reference Center for Rare Auto-immune and Systemic Diseases, Institut E3M, AP-HP, Pitié-Salpêtrière Hospital, Paris, France;

7. Université Pierre et Marie Curie University Paris 6, Paris, France;

8. Pediatric Hematology, Trousseau Hospital, APHP, Paris, France;

9. Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain;

10. Department of Pediatrics, Cincinnati Children’s Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH;

11. Leukemia Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY;

12. Feigin Center, Texas Children’s Cancer Center, Houston, TX;

13. Pathology Department, Pitié-Salpétrière Hospital, Paris, France;

14. Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY;

15. Necker Enfants Malades Hospital, AP-HP, Paris, France;

16. Institut Imagine, Sorbonne Paris Cité, Université Paris Descartes, Paris, France;

17. Division of Clínical Immunology, Hospital General Universitario and Health Research Institute “Gregorio Marañón,” Madrid, Spain;

18. Childhood Cancer Research Unit, Department of Women’s and Children’s Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden;

19. Department of Investigational Cancer Therapeutics (Phase I Clinical Trials Program), The University of Texas MD Anderson Cancer Center, Houston, TX;

20. Mount Sinai School of Medicine, New York, NY;

21. Pathology Department, University of Pittsburgh School of Medicine, Children’s Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA;

22. Dana-Farber Cancer Institute, Boston, MA;

23. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA;

24. Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA;

25. Division of Pulmonary, Saint Louis Hospital, Paris, France;

26. Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN; and

27. Clarient Pathology Services, Aliso Viejo, CA

Abstract

Abstract The histiocytoses are rare disorders characterized by the accumulation of macrophage, dendritic cell, or monocyte-derived cells in various tissues and organs of children and adults. More than 100 different subtypes have been described, with a wide range of clinical manifestations, presentations, and histologies. Since the first classification in 1987, a number of new findings regarding the cellular origins, molecular pathology, and clinical features of histiocytic disorders have been identified. We propose herein a revision of the classification of histiocytoses based on histology, phenotype, molecular alterations, and clinical and imaging characteristics. This revised classification system consists of 5 groups of diseases: (1) Langerhans-related, (2) cutaneous and mucocutaneous, and (3) malignant histiocytoses as well as (4) Rosai-Dorfman disease and (5) hemophagocytic lymphohistiocytosis and macrophage activation syndrome. Herein, we provide guidelines and recommendations for diagnoses of these disorders.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Reference95 articles.

1. Histiocytosis syndromes in children.;Writing Group of the Histiocyte Society;Lancet,1987

2. Human dendritic cell subsets.;Collin;Immunology,2013

3. Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny.;Guilliams;Nat Rev Immunol,2014

4. Association of both Langerhans cell histiocytosis and Erdheim-Chester disease linked to the BRAFV600E mutation.;Hervier;Blood,2014

5. Recurrent BRAF mutations in Langerhans cell histiocytosis.;Badalian-Very;Blood,2010

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