T cells expressing an anti–B-cell maturation antigen chimeric antigen receptor cause remissions of multiple myeloma

Author:

Ali Syed Abbas1,Shi Victoria2,Maric Irina3,Wang Michael4,Stroncek David F.5,Rose Jeremy J.2,Brudno Jennifer N.1,Stetler-Stevenson Maryalice6,Feldman Steven A.7,Hansen Brenna G.2,Fellowes Vicki S.2,Hakim Frances T.2,Gress Ronald E.2,Kochenderfer James N.2

Affiliation:

1. Center for Cancer Research, and

2. Experimental Transplantation and Immunology Branch, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD;

3. Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, MD;

4. University of Texas MD Anderson Cancer Center, Houston, TX;

5. Department of Transfusion Medicine, Clinical Center, NIH, Bethesda, MD;

6. Laboratory of Pathology, and

7. Surgery Branch, National Cancer Institute, NIH, Bethesda, MD

Abstract

Key Points Anti-BCMA T cells have impressive activity against MM.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Cited by 600 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Targeted immunotherapy: harnessing the immune system to battle multiple myeloma;Cell Death Discovery;2024-01-27

2. Fc receptor-like 5 (FCRL5)-directed CAR-T cells exhibit antitumor activity against multiple myeloma;Signal Transduction and Targeted Therapy;2024-01-12

3. The persistence and antitumor efficacy of CAR-T cells are modulated by tonic signaling within the CDR;International Immunopharmacology;2024-01

4. Chimeric Antigen Receptor Therapy in Multiple Myeloma;Manual of Hematopoietic Cell Transplantation and Cellular Therapies;2024

5. Proteasome Inhibitors in Multiple Myeloma;Hematology/Oncology Clinics of North America;2024-01

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3