SOX11 promotes tumor protective microenvironment interactions through CXCR4 and FAK regulation in mantle cell lymphoma-Reference-Cited by-同舟云学术

SOX11 promotes tumor protective microenvironment interactions through CXCR4 and FAK regulation in mantle cell lymphoma

Published:2017-07-27 Issue:4 Volume:130 Page:501-513
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Balsas Patricia¹²^ORCID,Palomero Jara¹^ORCID,Eguileor Álvaro¹²^ORCID,Rodríguez Marta Leonor¹,Vegliante Maria Carmela¹^ORCID,Planas-Rigol Ester¹³^ORCID,Sureda-Gómez Marta¹,Cid Maria C.¹³^ORCID,Campo Elias¹²⁴^ORCID,Amador Virginia¹²^ORCID

Affiliation:

1. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain;

2. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC); and

3. Vasculitis Research Unit, Department of Autoimmune Diseases and

4. Department of Anatomic Pathology, Hospital Clínic, University of Barcelona, Barcelona, Spain

Abstract

Key Points SOX11 regulates MCL homing and invasion via direct regulation of CXCR4 and FAK expression and PI3K/AKT and ERK1/2 signaling activation. SOX11 expression increases CAM-DR, contributing to a more aggressive MCL phenotype.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/130/4/501/1404829/blood776740.pdf

Reference51 articles.

1. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues;Swerdlow,2008

2. The 2016 revision of the World Health Organization classification of lymphoid neoplasms;Swerdlow;Blood,2016

3. Distinction between asymptomatic monoclonal B-cell lymphocytosis with cyclin D1 overexpression and mantle cell lymphoma: from molecular profiling to flow cytometry;Espinet;Clin Cancer Res,2014

4. Indolent mantle cell leukemia: a clinicopathological variant characterized by isolated lymphocytosis, interstitial bone marrow involvement, kappa light chain restriction, and good prognosis;Ondrejka;Haematologica,2011

5. Genomic and gene expression profiling defines indolent forms of mantle cell lymphoma;Fernàndez;Cancer Res,2010

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