A perspective on the selection of unrelated donors and cord blood units for transplantation-Reference-Cited by-同舟云学术

A perspective on the selection of unrelated donors and cord blood units for transplantation

Published:2012-07-12 Issue:2 Volume:120 Page:259-265
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Spellman Stephen R.¹,Eapen Mary²,Logan Brent R.³,Mueller Carlheinz⁴,Rubinstein Pablo⁵,Setterholm Michelle I.⁶,Woolfrey Ann E.⁷,Horowitz Mary M.²,Confer Dennis L.⁶,Hurley Carolyn K.⁸

Affiliation:

1. Center for International Blood and Marrow Transplant Research, Minneapolis, MN;

2. Center for International Blood and Marrow Transplant Research, Division of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI;

3. Center for International Blood and Marrow Transplant Research, Division of Biostatistics, Medical College of Wisconsin, Milwaukee, WI;

4. German National Bone Marrow Registry, Ulm, Germany;

5. National Cord Blood Program, New York Blood Center, New York, NY;

6. National Marrow Donor Program, Minneapolis, MN;

7. Fred Hutchinson Cancer Research Center, Seattle, WA; and

8. Department of Oncology, Georgetown University, Washington, DC

Abstract

Abstract Selection of a suitable graft for allogeneic hematopoietic stem cell transplantation involves consideration of both donor and recipient characteristics. Of primary importance is sufficient donor-recipient HLA matching to ensure engraftment and acceptable rates of GVHD. In this Perspective, the National Marrow Donor Program and the Center for International Blood and Marrow Transplant Research provide guidelines, based on large studies correlating graft characteristics with clinical transplantation outcomes, on appropriate typing strategies and matching criteria for unrelated adult donor and cord blood graft selection.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/120/2/259/1360519/zh802812000259.pdf

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