Lack of durable disease control with chemotherapy for mycosis fungoides and Sézary syndrome: a comparative study of systemic therapy

Author:

Hughes Charlotte F. M.12,Khot Amit1,McCormack Christopher23,Lade Stephen4,Westerman David A.124,Twigger Robert1,Buelens Odette1,Newland Kate1,Tam Constantine1,Dickinson Michael1,Ryan Gail5,Ritchie David12,Wood Colin1,Prince H. Miles12

Affiliation:

1. Division of Haematology and Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, Australia;

2. Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia;

3. Department of Dermatology, St. Vincent’s Hospital Department of Medicine, Melbourne, Australia;

4. Division of Pathology, Peter MacCallum Cancer Centre, Melbourne, Australia; and

5. Division of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia

Abstract

Key Points Chemotherapy results in a short median time to next treatment in patients with mycosis fungoides/Sézary syndrome. α-interferon achieves a superior time to next treatment compared with chemotherapy, regardless of stage.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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