The effect of donor characteristics on survival after unrelated donor transplantation for hematologic malignancy

Author:

Kollman Craig1,Spellman Stephen R.2,Zhang Mei-Jie34,Hassebroek Anna2,Anasetti Claudio5,Antin Joseph H.6,Champlin Richard E.7,Confer Dennis L.2,DiPersio John F.8,Fernandez-Viña Marcelo9,Hartzman Robert J.10,Horowitz Mary M.3,Hurley Carolyn K.11,Karanes Chatchada12,Maiers Martin13,Mueller Carlheinz R.14,Perales Miguel-Angel15,Setterholm Michelle13,Woolfrey Ann E.16,Yu Neng17,Eapen Mary318

Affiliation:

1. Jaeb Center for Health Research, Tampa, FL;

2. Center for International Blood and Marrow Transplant Research, National Marrow Donor Program/Be The Match, Minneapolis, MN;

3. Center for International Blood and Marrow Transplant Research and

4. Division of Biostatistics, Institute for Health and Society, Medical College of Wisconsin, Milwaukee, WI;

5. H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL;

6. Center for Hematologic Oncology, Dana-Farber Cancer Institute, Boston, MA;

7. Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX;

8. Barnes Jewish Hospital, St. Louis, MO;

9. Stanford Hospital & Clinics, Stanford, CA;

10. C.W. Bill Young Marrow Donor Recruitment and Research Program, Department of Defense Marrow Donor Program, Bone Marrow Research Directorate, Naval Medical Research Center, Department of the Navy, Washington, DC;

11. Georgetown University, Washington, DC;

12. City of Hope National Medical Center, Duarte, CA;

13. National Marrow Donor Program/Be The Match, Minneapolis, MN;

14. ZKRD-Zentrales Knochenmarkspender-Register Deutschland, Ulm, Germany;

15. Memorial Sloan-Kettering Cancer Center, New York, NY;

16. Fred Hutchinson Cancer Research Center, Seattle, WA;

17. American Red Cross Blood Services East Division, Dedham, MA; and

18. Department of Medicine, Medical College of Wisconsin, Milwaukee, WI

Abstract

Key Points Donor age and donor-recipient HLA match predict survival after hematopoietic cell transplantation.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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