R-MPV followed by high-dose chemotherapy with TBC and autologous stem-cell transplant for newly diagnosed primary CNS lymphoma-Reference-Cited by-同舟云学术

R-MPV followed by high-dose chemotherapy with TBC and autologous stem-cell transplant for newly diagnosed primary CNS lymphoma

Published:2015-02-26 Issue:9 Volume:125 Page:1403-1410
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Omuro Antonio¹,Correa Denise D.¹,DeAngelis Lisa M.¹,Moskowitz Craig H.²,Matasar Matthew J.²,Kaley Thomas J.¹,Gavrilovic Igor T.¹,Nolan Craig¹,Pentsova Elena¹,Grommes Christian C.¹,Panageas Katherine S.³,Baser Raymond E.³,Faivre Geraldine¹,Abrey Lauren E.¹,Sauter Craig S.²

Affiliation:

1. Department of Neurology,

2. Department of Medicine, and

3. Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY

Abstract

Key Points We conducted a phase-2 study in newly diagnosed PCNSL utilizing R-MPV and HDC with ASCT. Excellent disease control and OS (2-year PFS: 79%) were observed, with an acceptable toxicity profile and minimal neurotoxicity.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/125/9/1403/1388850/1403.pdf

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