Epidemiology of incident immune thrombocytopenia: a nationwide population-based study in France

Author:

Moulis Guillaume123ORCID,Palmaro Aurore23,Montastruc Jean-Louis2345,Godeau Bertrand6,Lapeyre-Mestre Maryse234,Sailler Laurent123

Affiliation:

1. Service de Médecine Interne, Centre Hospitalier Universitaire de Toulouse, Toulouse, France;

2. Université de Toulouse, UMR1027, Toulouse, France;

3. INSERM, UMR1027, Toulouse, France;

4. Service de Pharmacologie Médicale et Clinique, and

5. Centre Midi-Pyrénées de PharmacoVigilance, de Pharmacoépidémiologie et d’Informations sur le Médicament, Centre Hospitalier Universitaire de Toulouse, Toulouse, France; and

6. Service de Médecine Interne, Centre Hospitalier Universitaire Henri-Mondor, Assistance Publique-Hôpitaux de Paris, Centre de Référence des Cytopénies Auto-immunes de l'Adulte, Université Paris-Est-Créteil, Créteil, France

Abstract

Key Points Incidence of ITP was 2.9/100 000 person-years with age, seasonal, and regional variations; in adults, 18% were secondary. Severe (gastrointestinal or central nervous system) bleeding at ITP onset was rare (<1%); the risk increased with age.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Reference52 articles.

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2. The pathogenesis of immune thrombocytopaenic purpura.;Cooper;Br J Haematol,2006

3. ITP: a historical perspective.;Stasi;Br J Haematol,2011

4. The incidence of immune thrombocytopenic purpura in children and adults: A critical review of published reports.;Terrell;Am J Hematol,2010

5. Epidemiology of immune thrombocytopenic purpura in the General Practice Research Database.;Schoonen;Br J Haematol,2009

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