Infection-related mortality in children with acute lymphoblastic leukemia: an analysis of infectious deaths on UKALL2003-Reference-Cited by-全球学者库

Infection-related mortality in children with acute lymphoblastic leukemia: an analysis of infectious deaths on UKALL2003

Published:2014-08-14 Issue:7 Volume:124 Page:1056-1061
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

O’Connor David¹,Bate Jessica²,Wade Rachel³,Clack Rachel³,Dhir Sunita⁴,Hough Rachael⁵,Vora Ajay⁶,Goulden Nick⁷,Samarasinghe Sujith⁷

Affiliation:

1. Imperial College London, London, United Kingdom;

2. Institute of Child Health, University College London, United Kingdom;

3. Clinical Trial Service Unit, University of Oxford, Oxford, United Kingdom;

4. Great North Children's Hospital, Newcastle Upon Tyne, United Kingdom;

5. University College Hospital, London, United Kingdom;

6. Sheffield Children’s Hospital, Sheffield, United Kingdom; and

7. Great Ormond Street Hospital, London, United Kingdom

Abstract

Key Points Infection is the major cause of treatment-related mortality in pediatric acute lymphoblastic leukemia and is greatest during the induction phase. Children with Down syndrome are at high risk for infection-related mortality throughout all treatment phases, including the low-intensity maintenance phase.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/7/1056/1384059/1056.pdf

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