Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome-Reference-Cited by-同舟云学术

Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome

Published:2015-10-01 Issue:14 Volume:126 Page:1723-1728
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Weber Daniela¹,Oefner Peter J.²,Hiergeist Andreas³,Koestler Josef³,Gessner André³,Weber Markus⁴,Hahn Joachim¹,Wolff Daniel¹,Stämmler Frank⁵,Spang Rainer⁵,Herr Wolfgang¹,Dettmer Katja²,Holler Ernst¹

Affiliation:

1. Department of Hematology and Oncology, Internal Medicine III, University Medical Center, Regensburg, Germany;

2. Institute of Functional Genomics, University of Regensburg, Regensburg, Germany;

3. Institute of Clinical Microbiology and Hygiene and

4. Department of Orthopedic Surgery, University Medical Center, Regensburg, Germany; and

5. Statistical Bioinformatics, Institute of Functional Genomics, University of Regensburg, Regensburg, Germany

Abstract

Key Points Urinary 3-IS levels predict outcome after ASCT and are associated with antibiotics and NOD2/CARD15 variants.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/126/14/1723/1388980/1723.pdf

Reference34 articles.

1. Graft-versus-host disease.;Ferrara;Lancet,2009

2. Structure, function and diversity of the healthy human microbiome.;Human Microbiome Project Consortium;Nature,2012

3. Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation.;Arpaia;Nature,2013

4. The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis.;Smith;Science,2013

5. Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation.;Jenq;J Exp Med,2012

Cited by 159 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Microbiome metabolite quantification methods enabling insights into human health and disease;Methods;2024-02

2. Effect of GVHD on the gut and intestinal microflora;Transplant Immunology;2024-02

3. Gut microbiota, microbiota‐derived metabolites, and graft‐versus‐host disease;Cancer Medicine;2024-01-18

4. Randomized Double-Blind Phase II Trial of Fecal Microbiota Transplantation Versus Placebo in Allogeneic Hematopoietic Cell Transplantation and AML;Journal of Clinical Oncology;2023-12-01

5. Fecal short chain fatty acids and urinary 3-indoxyl sulfate do not discriminate between patients with Crohn´s disease and ulcerative colitis and are not of diagnostic utility for predicting disease severity;Lipids in Health and Disease;2023-10-03