A MALT lymphoma prognostic index

Author:

Thieblemont Catherine1,Cascione Luciano23,Conconi Annarita34,Kiesewetter Barbara5,Raderer Markus5,Gaidano Gianluca6,Martelli Maurizio7,Laszlo Daniele8,Coiffier Bertrand9,Lopez Guillermo Armando10,Torri Valter11,Cavalli Franco23,Johnson Peter W.12,Zucca Emanuele23

Affiliation:

1. Assistance Publique–Hôpitaux de Paris Hemato-Oncology Department, Saint Louis Hospital, Diderot University–Sorbonne Paris Cité, Paris, France;

2. Lymphoma Unit, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland;

3. Institute of Oncology Research, Bellinzona, Switzerland;

4. Unit of Hematology, Ospedale degli Infermi, Biella, Italy;

5. Division of Oncology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria;

6. Division of Hematology, Department of Translational Medicine, Università del Piemonte Orientale, Ospedale Maggiore della Carità, Novara, Italy;

7. Department of Cellular Biotechnologies and Hematology, Sapienza University, Rome, Italy;

8. European Institute of Oncology, Milan, Italy;

9. Centre Hospitalier Lyon-Sud, Pierre-Benite, France;

10. Department of Haematology, Hospital Clinic, Barcelona, Spain;

11. Clinical Research Methodology Laboratory, IRCCS–Mario Negri Institute, Milan, Italy; and

12. Cancer Research UK Center, Southampton General Hospital, Southampton, United Kingdom

Abstract

Key Points The MALT-IPI was built by using 401 patients in the IELSG-19 randomized trial and validated in an independent set (N = 633). This novel disease-specific index efficiently discriminates patient with good, intermediate, and poor outcomes.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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