Inhibitory effect of tumor cell–derived lactic acid on human T cells
Author:
Affiliation:
1. Department of Hematology and Oncology
2. Laboratory Center Bremen, Bremen, Germany
3. Institute of Functional Genomics, and
4. Institute of Pathology, University of Regensburg, Regensburg, Germany;
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/109/9/3812/1495419/zh800907003812.pdf
Reference43 articles.
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2. Warburg O. [On the facultative anaerobiosis of cancer cells and its use in chemotherapy]. Munch Med Wochenschr1961; 103:2504–2506.
3. Elson DA, Ryan HE, Snow JW, Johnson R, Arbeit JM. Coordinate up-regulation of hypoxia inducible factor (HIF)-1alpha and HIF-1 target genes during multi-stage epidermal carcinogenesis and wound healing. Cancer Res2000; 60:6189–6195.
4. Maxwell PH, Pugh CW, Ratcliffe PJ. Activation of the HIF pathway in cancer. Curr Opin Genet Dev2001; 11:293–299.
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