International, evidence-based consensus diagnostic criteria for HHV-8–negative/idiopathic multicentric Castleman disease

Author:

Fajgenbaum David C.1,Uldrick Thomas S.2,Bagg Adam3,Frank Dale3,Wu David4,Srkalovic Gordan5,Simpson David6,Liu Amy Y.1,Menke David7,Chandrakasan Shanmuganathan8,Lechowicz Mary Jo8,Wong Raymond S. M.9ORCID,Pierson Sheila1,Paessler Michele10,Rossi Jean-François11,Ide Makoto12,Ruth Jason13,Croglio Michael14,Suarez Alexander1,Krymskaya Vera15,Chadburn Amy16,Colleoni Gisele17,Nasta Sunita18,Jayanthan Raj19,Nabel Christopher S.20,Casper Corey21,Dispenzieri Angela22,Fosså Alexander23,Kelleher Dermot24,Kurzrock Razelle25,Voorhees Peter26,Dogan Ahmet27,Yoshizaki Kazuyuki28,van Rhee Frits29,Oksenhendler Eric30,Jaffe Elaine S.2,Elenitoba-Johnson Kojo S. J.3,Lim Megan S.3

Affiliation:

1. Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;

2. National Cancer Institute, National Institutes of Health, Bethesda, MD;

3. Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;

4. Department of Laboratory Medicine, University of Washington, Seattle, WA;

5. Sparrow Cancer Center, Edward W. Sparrow Hospital Association, Lansing, MI;

6. Division of Haematology, North Shore Hospital, Auckland, New Zealand;

7. Division of Hematology, Department of Medicine, and Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN;

8. Department of Medicine, Emory University School of Medicine, Atlanta, GA;

9. Sir Y.K. Pao Centre for Cancer and Department of Medicine & Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong;

10. Department of Pathology, Children’s Hospital of Philadelphia, Philadelphia, PA;

11. Department of Hematology, Hôpital Saint Éloi University Hospital, Montpellier, France;

12. Department of Hematology, Takamatsu Red Cross Hospital, Takamatsu, Kagawa, Japan;

13. Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA;

14. School of Medicine, Stony Brook University, Stony Brook, NY;

15. Division of Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;

16. Department of Pathology, Weill Cornell Medical College, New York, NY;

17. Departamento de Oncologia Clínica e Experimental, Universidade Federal de São Paulo, São Paulo, Brazil;

18. Division of Hematology/Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;

19. Department of Pediatrics, Texas Children’s Hospital, Houston, TX;

20. Department of Medicine, Brigham and Women’s Hospital, Boston, MA;

21. Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA;

22. Division of Hematology/Oncology, Mayo Clinic, Rochester, MN;

23. Department of Oncology, Oslo University Hospital–Norwegian Radium Hospital, Oslo, Norway;

24. Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada;

25. Center for Personalized Therapy and Clinical Trials Office, UC San Diego Moores Cancer Center, La Jolla, CA;

26. Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Carolinas HealthCare System, Charlotte, NC;

27. Departments of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY;

28. Department of Organic Fine Chemicals, The Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan;

29. Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, AR; and

30. Department of Clinical Immunology, Hôpital Saint-Louis, Paris, France

Abstract

Key Points An international panel established the first ever diagnostic criteria for iMCD based on review of 244 clinical cases and 88 tissue samples. The criteria require multicentric lymphadenopathy with defined histopathology, ≥2 clinical/laboratory changes, and exclusion of iMCD mimics.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

全球学者库

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"全球学者库"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前全球学者库共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2023 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3