Chronic myelogenous leukemia stem and progenitor cells demonstrate chromosomal instability related to repeated breakage-fusion-bridge cycles mediated by increased nonhomologous end joining
Author:
Affiliation:
1. Division of Hematopoietic Stem Cell and Leukemia Research, and
2. Departments of Cancer Biology,
3. Population Sciences, and
4. Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/119/26/6187/1497792/zh802612006187.pdf
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4. Chronic myeloid leukemia: mechanisms of blastic transformation.;Perrotti;J Clin Invest,2010
5. Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes no. 5 and 7.;Le Beau;J Clin Oncol,1986
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