Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment
Author:
Affiliation:
1. Department of Pathology,
2. Department of Radiation and Cellular Oncology/Ludwig Center for Metastasis Research, and
3. Department of Surgery, University of Chicago, IL
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/114/3/589/1321033/zh802909000589.pdf
Reference29 articles.
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3. Radiation-induced, immunologically mediated regression of an established tumor as an example of successful therapeutic immunomanipulation: preferential elimination of suppressor T cells allows sustained production of effector T cells.;North;J Exp Med,1986
4. Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer.;Demaria;Clin Cancer Res,2005
5. Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions.;Ohuchida;Cancer Res,2004
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