Epcoritamab Monotherapy Provides Deep and Durable Responses Including Minimal Residual Disease (MRD) Negativity: Novel Subgroup Analyses in Patients with Relapsed/Refractory (R/R) Large B-Cell Lymphoma (LBCL)

Author:

Phillips Tycel1,Thieblemont Catherine23,Ghesquieres Herve4,Cheah Chan Y.5,Clausen Michael Roost6,Cunningham David7,Do Young Rok8,Feldman Tatyana A.9,Gasiorowski Robin10,Jurczak Wojciech11,Kim Tae Min12,Lewis David John1314,van der Poel Marjolein15161718,Poon Michelle Limei19,Kilavuz Nurgul20,Cota Stirner Mariana21,Soong David20,Chiu Christopher22,Chen Menghui20,Sacchi Mariana20,Elliot Brian20,Hutchings Martin23,Lugtenburg Pieternella24

Affiliation:

1. 1University of Michigan Comprehensive Cancer Center, Ann Arbor, MI

2. 2APHP, Saint-Louis Hospital, Paris, France

3. 3Université de Paris, Paris, France

4. 4Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre-Bénite, France

5. 5Sir Charles Gairdner Hospital, Nedlands, Australia

6. 6Vejle Hospital, Vejle, Denmark

7. 7The Royal Marsden NHS Foundation Trust, London, United Kingdom

8. 8Keimyung University Dongsan Medical Center, Daegu, Korea, Republic of (South)

9. 9Hackensack Meridian Health Hackensack University Medical Center, Hackensack, NJ

10. 10Concord Hospital, University of Sydney, Concord, Australia

11. 11MSC National Research Institute of Oncology, Krakow, Poland

12. 12Seoul National University Hospital, Seoul, Korea, Republic of (South)

13. 13University Hospitals Plymouth NHS Trust, Plymouth, United Kingdom

14. 14Derriford Hospital, Plymouth, United Kingdom

15. 15Maastricht University Medical Center, Maastricht, Netherlands

16. 16On behalf of the Lunenburg Lymphoma Phase I/II Consortium-HOVON/LLPC, Maastricht, Netherlands

17. 17GROW School for Oncology and Developmental Biology, Maastricht, Netherlands

18. 18Department of Hematology, Maastricht University Medical Center, Maastricht, Netherlands

19. 19National University Hospital, Singapore, Singapore

20. 20Genmab, Princeton, NJ

21. 21AbbVie, North Chicago, IL

22. 22Translational Research and Precision Medicine Operations, Genmab, Princeton, NJ

23. 23Rigshospitalet - Copenhagen University Hospital, Copenhagen, Denmark

24. 24Department of Hematology, On behalf of the HOVON lymphoma working group, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, Netherlands

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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