Intracranial hemorrhage in patients with brain metastases treated with therapeutic enoxaparin: a matched cohort study

Author:

Donato Jessica1,Campigotto Federico2,Uhlmann Erik J.3,Coletti Erika45,Neuberg Donna2ORCID,Weber Griffin M.6,Zwicker Jeffrey I.45

Affiliation:

1. Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA;

2. Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA; and

3. Department of Neurology,

4. Division of Hemostasis and Thrombosis,

5. Division of Hematology and Oncology, and

6. Interdisciplinary Medicine and Biotechnology, Center for Biomedical Informatics, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

Abstract

Key Points Significant intracranial hemorrhage occurs in 20% to 50% of patients with metastatic brain tumors. Therapeutic anticoagulation in patients with brain metastasis did not increase the risk for intracranial hemorrhage.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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