High prevalence of red blood cell alloimmunization in sickle cell disease despite transfusion from Rh-matched minority donors-Reference-Cited by-同舟云学术

High prevalence of red blood cell alloimmunization in sickle cell disease despite transfusion from Rh-matched minority donors

Published:2013-08-08 Issue:6 Volume:122 Page:1062-1071
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Chou Stella T.¹,Jackson Tannoa¹,Vege Sunitha²,Smith-Whitley Kim¹,Friedman David F.¹³,Westhoff Connie M.²

Affiliation:

1. Division of Hematology, The Children’s Hospital of Philadelphia, Philadelphia, PA;

2. Immunohematology and Genomics Laboratory, New York Blood Center, New York City, NY; and

3. Department of Pathology and Laboratory Medicine, The Children’s Hospital of Philadelphia, Philadelphia, PA

Abstract

Key Points Rh serologic phenotype–matched transfusions from minority donors do not prevent all Rh alloimmunization in patients with SCD. Variant RH genes are common in patients with SCD and contribute to Rh alloimmunization and transfusion reactions.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/6/1062/1375013/1062.pdf

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4. Clinical significance of RBC alloantibodies and autoantibodies in sickle cell patients who received transfusions.;Aygun;Transfusion,2002

5. Predicting the effect of transfusing only phenotype-matched RBCs to patients with sickle cell disease: theoretical and practical implications.;Castro;Transfusion,2002

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