Thalidomide corrects impaired mesenchymal stem cell function in inducing tolerogenic DCs in patients with immune thrombocytopenia-Reference-Cited by-同舟云学术

Thalidomide corrects impaired mesenchymal stem cell function in inducing tolerogenic DCs in patients with immune thrombocytopenia

Published:2013-09-19 Issue:12 Volume:122 Page:2074-2082
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Ma Ji¹,Ning Yun-na²,Xu Miao¹,Hou Yu³,Wang Ning¹,Hou Xiao-yan¹,Yu Ying-yi³,Li Hui¹,He Wei-dong⁴,Shao Lin-lin¹,Zhou Hai¹,Min Ya-nan¹,Liu Xin-guang¹,Shi Yan¹,Qin Ping¹,Guo Cheng-shan¹,Hou Ming¹⁵,Peng Jun¹⁵

Affiliation:

1. Department of Hematology, Qilu Hospital, and

2. Center for Reproductive Medicine, Shandong University, Jinan, China;

3. Medical School of Shandong University, Jinan, China;

4. Department of Blood Cell Components Separation, Blood Center of Shandong Province, Jinan, China; and

5. Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Jinan, China

Abstract

Key Points The impaired function of MSCs in proliferation ability and in inducing tolerogenic DCs may play a role in the pathogenesis of ITP. The effect of THD in correcting dysfunctions of MSCs may suggests a therapeutic potential of THD in ITP patients.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/12/2074/1368829/2074.pdf

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