Plasminogen replacement therapy for the treatment of children and adults with congenital plasminogen deficiency-Reference-Cited by-同舟云学术

Plasminogen replacement therapy for the treatment of children and adults with congenital plasminogen deficiency

Published:2018-03-22 Issue:12 Volume:131 Page:1301-1310
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Shapiro Amy D.¹,Nakar Charles¹,Parker Joseph M.²,Albert Gary R.²,Moran John E.³,Thibaudeau Karen³,Thukral Neelam¹,Hardesty Brandon M.¹,Laurin Pierre³,Sandset Per Morten⁴

Affiliation:

1. Indiana Hemophilia and Thrombosis Center, Indianapolis, IN;

2. Prometic Biotherapeutics Inc., Rockville, MD;

3. Prometic Life Sciences, Laval, QC, Canada; and

4. Department of Hematology, Oslo University Hospital and University of Oslo, Oslo, Norway

Abstract

Key Points This is the first trial to evaluate the clinical utility of Glu-plasminogen in children and adults with congenital plasminogen deficiency. Glu-plasminogen achieves physiological levels of plasminogen activity coinciding with improved clinical efficacy and disease management.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/131/12/1301/1405457/blood806729.pdf

Reference23 articles.

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4. Ligneous conjunctivitis: an autosomal recessive disorder;Bateman;J Pediatr Ophthalmol Strabismus,1986

5. Ligneous conjunctivitis;Schuster;Surv Ophthalmol,2003

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