CXCL13 plus interleukin 10 is highly specific for the diagnosis of CNS lymphoma-Reference-Cited by-同舟云学术

CXCL13 plus interleukin 10 is highly specific for the diagnosis of CNS lymphoma

Published:2013-06-06 Issue:23 Volume:121 Page:4740-4748
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Rubenstein James L.¹,Wong Valerie S.¹,Kadoch Cigall¹,Gao Hua-Xin¹,Barajas Ramon²,Chen Lingjing¹,Josephson S. Andrew³,Scott Brian³,Douglas Vanja³,Maiti Mekhala¹,Kaplan Lawrence D.¹,Treseler Patrick A.⁴,Cha Soonmee²,Hwang Jimmy H.⁵,Cinque Paola⁶,Cyster Jason G.⁷,Lowell Clifford⁸

Affiliation:

1. Division of Hematology/Oncology, Helen Diller Family Comprehensive Cancer Center,

2. Department of Radiology and Biomedical Imaging,

3. Department of Neurology,

4. Department of Pathology, and

5. Biostatistics and Computational Biology Core, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA;

6. Department of Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy; and

7. Department of Microbiology and Immunology, Howard Hughes Medical Institute, and

8. Department of Laboratory Medicine, University of California, San Francisco, CA

Abstract

Key PointsCXCL13 and CXCL12 mediate chemotaxis of CNS lymphoma cells, and CXCL13 concentration in CSF is prognostic. CXCL13 plus IL-10 is highly specific for the diagnosis of CNS lymphoma.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/23/4740/1366324/4740.pdf

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