Increased Activity of Some Folic Acid Enzyme Systems in Infectious Mononucleosis-Reference-Cited by-同舟云学术

Increased Activity of Some Folic Acid Enzyme Systems in Infectious Mononucleosis

Published:1962-05-01 Issue:5 Volume:19 Page:587-592
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

BERTINO JOSEPH R.¹²,SIMMONS BARBARA M.¹³,DONOHUE DENNIS M.¹³

Affiliation:

1. King County Central Blood Bank, and the Department of Medicine, University of Washington School of Medicine, Seattle, Wash.

2. Yale University School of Medicine, New Haven, Conn.

3. Department of Medicine, University of Washington School of Medicine, Seattle, Wash.

Abstract

Abstract Increased levels of activity for the formate activating enzyme and N5,N10-methylene FH4 dehydrogenase have been found in the leukocytes from patients with infectious mononucleosis; in addition dihydrofolic reductase, an enzyme not found in mature circulating leukocytes, has been detected in infectious mononucleosis cells. Glucose-6-phosphate dehydrogenase activity is less in infectious mononucleosis leukocytes than in normal leukocytes. These findings are similar to the results obtained in acute and chronic myelogenous leukemia and indicate that the leukocytes seen in infectious mononucleosis have the enzymatic apparatus associated with synthesis of DNA.

Publisher

American Society of Hematology

Link

http://ashpublications.org/blood/article-pdf/19/5/587/570628/587.pdf

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Potential Viral Etiology of Human Tumors;Handbuch der allgemeinen Pathologie;1975

2. Die infektiöse Mononucleose;Blut und Blutkrankheiten;1974

3. Formyltetrahydrofolate Synthetas;CRC Critical Reviews in Biochemistry;1973-01

4. Synthesis and Metabolism of DNA and DNA Precursors by Human Normal and Leukemic Leukocytes;Acta Haematologica;1971

5. Infektiöse Mononukleose^*¹;DMW - Deutsche Medizinische Wochenschrift;1970-04