Affiliation:
1. From the Oncology Center, Johns Hopkins University School of Medicine, Baltimore, MD.
Abstract
Allogeneic stem cell transplantation (SCT) is now a commonplace procedure. Clinicians who care for patients with hematologic malignancies and aplastic anemia are almost certain to follow up patients after SCT. This review is intended to help clinicians observe patients for probably the most important late complication of SCT, chronic graft-versus-host disease (GVHD). It reviews the pathophysiology, risk factors, clinical manifestations, evaluation, treatment, and supportive care of chronic GVHD.
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Reference34 articles.
1. Differential cytokine expression in acute and chronic murine graft-versus-host disease.;Allen;Eur J Immunol.,1993
2. Preferential activation of Th2 cells in chronic murine graft-versus-host reaction.;de Wit;J Immunol.,1993
3. Cyclosporine-induced syngeneic graft-versus-host disease: recognition of self-MHC class II antigens in vivo.;Hess;Transplant Proc.,1993
4. Minor histocompatibility antigens.;Perreault;Blood.,1990
5. Graft-versus-host disease: the influence of type 1 and type 2 T cell cytokines [review].;Ferrara;Transfus Med Rev.,1998
Cited by
206 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献