Phase 1 study of lenzilumab, a recombinant anti–human GM-CSF antibody, for chronic myelomonocytic leukemia
Author:
Affiliation:
1. Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN;
2. Department of Hematologic Malignancies, Moffitt Cancer Center, Tampa, FL;
3. Humanigen Inc, Burlingame, CA; and
4. BeiGene, San Mateo, CA
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/136/7/909/1752091/bloodbld2019004352.pdf
Reference11 articles.
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3. Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents;Merlevede;Nat Commun,2016
4. Suboptimal response rates to hypomethylating agent therapy in chronic myelomonocytic leukemia; a single institutional study of 121 patients;Coston;Am J Hematol,2019
5. GM-CSF-dependent pSTAT5 sensitivity is a feature with therapeutic potential in chronic myelomonocytic leukemia;Padron;Blood,2013
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