PICALM Gene Methylation in Blood of Alzheimer’s Disease Patients Is Associated with Cognitive Decline

Author:

Mercorio Roberta1,Pergoli Laura1,Galimberti Daniela2,Favero Chiara1,Carugno Michele1,Dalla Valle Elisabetta2,Barretta Francesco1,Cortini Francesca1,Scarpini Elio2,Valentina Valentina Bollati1,Pesatori Angela Cecilia13

Affiliation:

1. EPIGET - Epidemiology, Epigenetics and Toxicology Lab - Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy

2. Department of Pathophysiology and Transplantation, Dino Ferrari Center, University of Milan, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy

3. Epidemiology Unit, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

Reference47 articles.

1. Alzheimer’s disease;Scheltens;Lancet,2016

2. Neuronal loss, neurofibrillary tangles and granulovacuolar degeneration in the hippocampus with ageing and dementia. A quantitative study;Ball;Acta Neuropathol,1977

3. Association of total tau and phosphorylated tau 181 protein levels in cerebrospinal fluid with cerebral atrophy in mild cognitive impairment and Alzheimer disease;Thomann;J Psychiatry Neurosci,2009

4. Cerebrospinal fluid tau levels in Alzheimer’s disease are elevated when compared with vascular dementia but do not correlate with measures of cerebral atrophy;Schonknecht;Psychiatry Res,2003

5. Advancing research diagnostic criteria for Alzheimer’s disease: The IWG-2 criteria;Dubois;Lancet Neurol,2014

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