Deletion of the Cathepsin B Gene Improves Memory Deficits in a Transgenic Alzheimer's Disease Mouse Model Expressing AβPP Containing the Wild-Type β-Secretase Site Sequence

Author:

Kindy Mark S.123,Yu Jin1,Zhu Hong1,El-Amouri Salim S.4,Hook Vivian5,Hook Gregory R.6

Affiliation:

1. Department of Neurosciences, Medical University of South Carolina, Charleston, SC, USA

2. Ralph H. Johnson VA Medical Center, Charleston, SC, USA

3. Applied Neurotechnology, Inc., Charleston, SC, USA

4. Division of Experimental Hematology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA

5. Skaggs School of Pharmacy and Pharmaceutical Sciences and Departments of Neurosciences, Pharmacology and Medicine, University of California, San Diego, La Jolla, CA, USA

6. American Life Science Pharmaceuticals, San Diego, CA, USA

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

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