Blood Flow to the Spleen is Altered in a Mouse Model of Spinal Muscular Atrophy

Author:

Deguise Marc-Olivier123,Beauvais Ariane1,Schneider Bernard L.45,Kothary Rashmi1236

Affiliation:

1. Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

2. Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada

3. Centre for Neuromuscular Disease, University of Ottawa, Ottawa, Ontario, Canada

4. Bertarelli Foundation Gene Therapy Platform, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1202 Geneva, Switzerland

5. Brain Mind Institute, 27218 Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

6. Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada

Publisher

IOS Press

Subject

Clinical Neurology,Neurology

Reference33 articles.

1. Identification and characterization of a spinal muscular atrophy-determining gene;Lefebvre;Cell,1995

2. Spinal muscular atrophy: going beyond the motor neuron;Hamilton;Trends Mol Med,2013

3. Immune dysregulation may contribute to disease pathogenesis in spinal muscular atrophy mice;Deguise;Hum Mol Genet,2017

4. SMN deficiency negatively impacts red pulp macrophages and spleen development in mouse models of spinal muscular atrophy;Khairallah;Hum Mol Genet,2017

5. Survival of motor neurone protein is required for normal postnatal development of the spleen;Thomson;J Anat,2017

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