Cannabinoid effects in the microvasculature – CB, or not CB? That is the question! A mini-review-Reference-Cited by-同舟云学术

Cannabinoid effects in the microvasculature – CB, or not CB? That is the question! A mini-review

Published:2023-04-07 Issue:3 Volume:83 Page:287-292
ISSN:1386-0291
Container-title:Clinical Hemorheology and Microcirculation
language:
Short-container-title:CH

Author:

Lehmann Christian¹²³⁴⁵,Zhou Juan¹

Affiliation:

1. Department of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, NS, Canada

2. Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada

3. Department of Pharmacology, Dalhousie University, Halifax, NS, Canada

4. Department of Physiology and Biophysics, Dalhousie University, Halifax, NS, Canada

5. Department of Computer Science, Dalhousie University, Halifax, NS, Canada

Abstract

Cannabinoids play critical roles in human pathophysiology through the cannabinoid (CB) receptors and non-CB receptors on variety of cells, tissues, and organs. Microvasculature with the inside bloodstream containing the plasmatic and cellular components exerts multiple functions in maintaining tissue and organ physiology through microcirculation. This review focusses on the impact of cannabinoids on the microvasculature, including mechanisms mediated by both CB receptor-related pathways and CB receptor-independent pathways.

Publisher

IOS Press

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Hematology,Physiology

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