Genetic advancement in the detection of Systemic Lupus Erythematosus (SLE)

Author:

Singh Akshat Pratap1,Shaikh Mohammad Kamran2,Borker Anjali3,Bandre Gulshan4

Affiliation:

1. Datta Meghe Medical College, Nagpur. Datta Meghe Institute of Higher Education and Research (DU) Sawangi, Wardha, India

2. Community Medicine, Datta Meghe Medical College, Nagpur. Datta Meghe Institute of Higher Education and Research (DU) Sawangi, Wardha, India

3. Jawaharlal Nehru Medical College, Wardha. Datta Meghe Institute of Higher Education and Research (DU) Sawangi, Wardha, India

4. JRF Microbiology, Jawaharlal Nehru Medical College, Wardha. Datta Meghe Institute of Higher Education and Research (DU) Sawangi, Wardha, India

Abstract

The disease lupus, also known as systemic lupus erythematosus (SLE), is an autoimmune condition, chronic in nature, that can affect any organ in the body. The immune system of the body becomes hyperactive in lupus, attacking normal tissues and organs such as the skin, skeletal, renal, brain, heart, lungs, and blood. Normally, the immunologic response protects the body against outside susceptibilities. Periods of illness, known as flares, and times of wellness, known as remissions, are characteristics of lupus. Lupus is challenging to diagnose since its symptoms are vastly adherent and often mistaken for those of other illnesses. The presence of complexities in this illness cannot be proven with a single laboratory test. Lupus has no recognised cause or treatment as of yet. However, research is going on to achieve improved health outcomes, and early identification and treatment are essential. Lupus has no recognised cause or treatment as of yet. Early detection and treatment, which can typically reduce a disease’s severity and course, are essential to enhancing health outcomes. NSAIDs, antimalarials, and steroids (including cortisone and others) are widely used to treat lupus. Patients with lupus may also receive cytotoxic chemotherapy comparable to chemotherapy used to treat cancer. Patients with lupus may also receive cytotoxic chemotherapy comparable to chemotherapy used to treat cancer. This well-known and respected resource has a new edition that blends basic and clinical science to present a translational medicine concept. A helpful resource for professionals in the diagnosis and treatment of Systemic Lupus Erythematous patients, SLE serves as a reference for hospital libraries and as a tool for measuring clinical activity for drug development and fundamental research. Beautifully depicted and in full colour throughout Basic science part has been enhanced to let readers concentrate on the most recent molecular medicine techniques and how they affect the expression and treatment of diseases.

Publisher

IOS Press

Subject

Molecular Biology,Applied Microbiology and Biotechnology,Biotechnology

Reference35 articles.

1. Current Treatment Approach, Emerging Therapies and New Horizons in Systemic Lupus Erythematosus;Athanassiou;Life Basel Switz,2023

2. Knowledge and Awareness of Systemic Lupus Erythematosus Among the Population of Makkah, Saudi Arabia: A Cross-Sectional Study;Radhwi;Cureus,2023

3. A systematic review and meta-analysis of efficacy and safety of Romosozumab in postmenopausal osteoporosis;Singh;Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA,2022

4. Medical therapy for systemic lupus erythematosus;Taylor;J Miss State Med Assoc,2011

5. Immunological pathogenesis and treatment of systemic lupus erythematosus;Pan;World J Pediatr WJP,2020

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