1. Faculty of Health and Applied Sciences, University of the West of England, Bristol, UK
2. Research, Audit and Improvement Department, South Western Ambulance Service NHS Foundation Trust, Exeter, UK
3. Department of Surgery and Cancer, Imperial College Healthcare NHS Trust, London, UK
4. Clinical Trials and Evaluation Unit, Bristol Trials Centre, University of Bristol, Bristol, UK
5. Bristol Medical School, University of Bristol, Bristol, UK
6. Department of Anaesthesia, Royal United Hospital, Bath, UK
7. National Institute for Health and Care Research Applied Research Collaboration West (NIHR ARC West), Bristol, UK
8. Health Economic Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK
9. National Institute for Health and Care Research Oxford Biomedical Research Centre, Oxford, UK
10. Intensive Care Unit, University Hospitals Bristol NHS Foundation Trust, Bristol, UK