Exceptional Response to Bromodomain and Extraterminal Domain Inhibitor Therapy With BMS-986158 in <i>BRD4-NUTM1</i> NUT Carcinoma Harboring a <i>BRD4</i> Splice Site Mutation-Reference-Cited by-同舟云学术

Exceptional Response to Bromodomain and Extraterminal Domain Inhibitor Therapy With BMS-986158 in BRD4-NUTM1 NUT Carcinoma Harboring a BRD4 Splice Site Mutation

Published:2023-06 Issue:7 Volume: Page:
ISSN:2473-4284
Container-title:JCO Precision Oncology
language:en
Short-container-title:JCO Precision Oncology

Author:

Cheng Michael L.¹²^ORCID,Huang Yeying³,Luong Nhi³,LoPiccolo Jaclyn¹²,Nishino Mizuki⁴⁵^ORCID,Sholl Lynette M.³^ORCID,Chirieac Lucian R.³^ORCID,Santucci Alison D.¹⁶^ORCID,Rabin Michael S.¹²,Jänne Pasi A.¹²^ORCID,Coker Shodeinde⁷^ORCID,Diamond Jennifer R.⁸^ORCID,Hilton John⁹^ORCID,Shapiro Geoffrey I.²^ORCID,French Christopher A.³

Affiliation:

1. Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA

2. Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

3. Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

4. Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

5. Department of Imaging, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

6. Boston Medical Center, Boston, MA

7. Bristol Myers Squibb, Lawrenceville, NJ

8. University of Colorado Cancer Center, Aurora, CO

9. Division of Medical Oncology, Ottawa Hospital, Ottawa, ON

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

Link

https://ascopubs.org/doi/pdfdirect/10.1200/PO.22.00633

Reference28 articles.

1. BRD4 Bromodomain Gene Rearrangement in Aggressive Carcinoma with Translocation t(15;19)

2. Primary Pulmonary NUT Midline Carcinoma: Clinical, Radiographic, and Pathologic Characterizations

3. Report of the First International Symposium on NUT Carcinoma

4. The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis

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