SARCOIDOSIS. NEW COVID-19 INFECTION AND VACCINATION ISSUES
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Published:2021-08
Issue:4
Volume:14
Page:48-57
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ISSN:2071-0240
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Container-title:The Bulletin of Contemporary Clinical Medicine
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language:
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Short-container-title:VSKM
Author:
VIZEL ALEXANDER A., ,VIZEL IRINA YU.,KOSTINOV MIKHAIL P.,AMIROV NAIL B., , ,
Abstract
Aim.The aim of the study was to analyze the available publications devoted to the problem of the combination of the new infection COVID19 and sarcoidosis, and the issues of vaccination in sarcoidosis. The urgency of the problem is dictated by the need to prevent infections in such granulomatosis as well as by the growing worldwide experience of vaccination against COVID19. Material and methods. An analytical review of 50 publications in the scientific medical literature was performed. Results and discussion. A review of publications has shown that there is already an accumulation of data on the vaccination of sarcoidosis patients against other manageable infections. We did not come across any papers indicating that vaccinating sarcoidosis patients is dangerous. It remains intriguing to consider any antigenic factors as triggers of sarcoidosis in genetically predisposed individuals. But even from this point of view, an antigenically complete pathogen can play both the role of a trigger and the development of infection in a sarcoidosis patient with drug immunosuppression than a vaccine strain. Regarding vaccination in general and against COVID19 in particular in advanced sarcoidosis is the statement that the patient should be vaccinated before the start of immunomodulating therapy. Conclusion. From the point of evidencebased medicine, the question of the safety and efficacy of vaccinating patients with sarcoidosis remains open. The current transnational position is based on the extrapolation of the experience with other vaccines for sarcoidosis and the use of COVID19 vaccines for other diseases. Understanding COVID19 as a severe lifethreatening disease makes vaccination justified, the key position being to assess potential risks, to correct immunosuppressive therapy and, if possible, to vaccinate before the use of hormones and immunosuppressants.
Publisher
Contemporary Clinical Medicine
Cited by
1 articles.
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1. Outpatient management of sarcoidosis in the COVID-19 pandemic;Bulletin Physiology and Pathology of Respiration;2023-09-28