Continuous flow synthesis of a pharmaceutical intermediate: a computational fluid dynamics approach-Reference-Cited by-同舟云学术

Continuous flow synthesis of a pharmaceutical intermediate: a computational fluid dynamics approach

Published:2019 Issue:3 Volume:4 Page:634-642
ISSN:2058-9883
Container-title:Reaction Chemistry & Engineering
language:en
Short-container-title:React. Chem. Eng.

Author:

Armstrong Cameron T.¹²³⁴^ORCID,Pritchard Cailean Q.⁵⁶⁷⁸^ORCID,Cook Daniel W.¹²³⁴^ORCID,Ibrahim Mariam¹²³⁴^ORCID,Desai Bimbisar K.¹²³⁴^ORCID,Whitham Patrick J.⁹¹⁰¹¹,Marquardt Brian J.⁹¹⁰¹¹,Chen Yizheng¹²³⁴,Zoueu Jeremie T.¹²³⁴,Bortner Michael J.⁵⁶⁷⁸^ORCID,Roper Thomas D.¹²³⁴^ORCID

Affiliation:

1. Chemical and Life Science Engineering

2. Virginia Commonwealth University

3. Richmond

4. 23219 USA

5. Department of Chemical Engineering and Macromolecules Innovation Institute

6. Virginia Polytechnic Institute and State University

7. Blacksburg

8. 24061 USA

9. MarqMetrix, Inc.

10. Seattle

11. 98103 USA

Abstract

Computational fluid dynamic and experimental approaches have been compared in the prediction of reaction performance in the preparation of a pharmaceutical intermediate.

Funder

Bill and Melinda Gates Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RE/C8RE00252E

Reference30 articles.

1. Applying Flow Chemistry: Methods, Materials, and Multistep Synthesis

2. The Hitchhiker’s Guide to Flow Chemistry

3. Continuous flow multi-step organic synthesis