Affiliation:
1. Department of Pharmacy, National University of Singapore, 4 Science Dr 2, Singapore 117544, Singapore
Abstract
This report highlights recent reports of bacteria-derived cyclophane-containing peptides from radical SAM/SPASM enzymes. The strategies for discovery, structures of the products, bioactivity, mechanism of formation, and synthesis are discussed.
Funder
Ministry of Education - Singapore
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Biochemistry