Construction of engineered 3D islet micro-tissue using porcine decellularized ECM for the treatment of diabetes-Reference-Cited by-同舟云学术

Construction of engineered 3D islet micro-tissue using porcine decellularized ECM for the treatment of diabetes

Published:2023 Issue:16 Volume:11 Page:5517-5532
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Wang Xiaocheng¹²,Jin Lijuan²³,Liu Wenyu²³,Stingelin Lukas²,Zhang Pan¹,Tan Zhikai²³^ORCID

Affiliation:

1. Department of Infectious Diseases, Third Xiangya Hospital, Central South University, Changsha, 410008, China

2. College of Biology, Hunan University, Changsha, 410082, China

3. Shenzhen Institute, Hunan University, Shenzhen, 518000, China

Abstract

3D islet micro-tissues are fabricatied using porcine decellularized ECM, which could be used not only for islet micro-tissue culture in vitro, but also have great promise for islet transplantation for the treatment of diabetes.

Funder

Key Project of Research and Development Plan of Hunan Province

Fudan University

Shanghai Key Laboratory of Peripheral Nerve and Microsurgery

Natural Science Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D3BM00346A

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2. Genetics of diabetes mellitus and diabetes complications

3. Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models

4. Clinical pancreatic islet transplantation

5. A human pancreatic ECM hydrogel optimized for 3-D modeling of the islet microenvironment

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