Integrated gut microbiota and fecal metabolome analyses of the effect of Lycium barbarum polysaccharide on d-galactose-induced premature ovarian insufficiency

Author:

Zheng Huili1,Liang Xiaofei1,Zhou Hongli1,Zhou Tong1,Liu Xinhui1,Duan Jialun1,Duan Jin-ao1ORCID,Zhu Yue1ORCID

Affiliation:

1. Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, and Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing 210023, China

Abstract

Lycium barbarum polysaccharides improve ovarian reserve by regulating gut microbiota and related metabolism, which provide beneficial support for its applications in treating premature ovarian insufficiency.

Funder

National Natural Science Foundation of China

Key Research and Development Program of Ningxia

State Administration of Traditional Chinese Medicine of the People's Republic of China

Jiangsu Provincial Key Research and Development Program

Major Projects of Natural Sciences of University in Jiangsu Province of China

Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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