Metal-free synthesis of alkynyl alkyl selenides via three-component coupling of terminal alkynes, Se, and epoxides

Author:

Wu Ge1234ORCID,Min Lin5634,Li Hongchen5634,Gao Wenxia5634ORCID,Ding Jinchang5634,Huang Xiaobo5634ORCID,Liu Miaochang5634,Wu Huayue5634

Affiliation:

1. School of Pharmaceutical Science

2. Wenzhou Medical University

3. Wenzhou 325035

4. People's Republic of China

5. College of Chemistry and Materials Engineering

6. Wenzhou University

Abstract

A metal-free three-component coupling reaction of alkynes, Se powder and epoxides is described, providing an efficient, straightforward route for the preparation of alkynyl alkyl selenides via a double C–Se bond formation process.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Wenzhou Medical University

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

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