DNA-compatible synthesis of enaminones <i>via</i> amination of allenic ketones-Reference-Cited by-同舟云学术

DNA-compatible synthesis of enaminones via amination of allenic ketones

Published:2023 Issue:16 Volume:10 Page:4105-4110
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Wang Huihong¹²^ORCID,Fan Xiaohong¹²^ORCID,Chen Teng¹,Li Yangfeng¹³^ORCID,Zhang Gong¹³^ORCID,Fang Wei²,Li Yizhou¹³⁴^ORCID

Affiliation:

1. Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, 401331 Chongqing, P. R. China

2. Pharmaceutical Department, Chongqing University Three Gorges Hospital, Chongqing University, 404100 Chongqing, P. R. China

3. Chemical Biology Research Center, School of Pharmaceutical Sciences, Chongqing University, 401331 Chongqing, China

4. Beijing National Laboratory for Molecular Sciences, 100190 Beijing, China

Abstract

We presented an efficient synthetic route for DNA-compatible generation of enaminones and subsequent transformations to polyfunctionalized benzenes, facilitating chemically diverse DNA-encoded library construction.

Funder

Chongqing Postdoctoral Science Foundation

High-end Foreign Experts Recruitment Plan of China

Fundamental Research Funds for the Central Universities

Natural Science Foundation of Chongqing

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D3QO00901G