Copper-catalyzed ring-opening sulfonylation of cyclopropanols via the insertion of sulfur dioxide toward the synthesis of γ-keto aryl sulfones

Abstract

A copper-catalyzed three-component sulfonylation reaction is presented. This protocol provides easy and straightforward access to structurally diverse γ-keto aryl sulfones with good yields, mild reaction conditions, low catalyst loading, and good functional group tolerance.