Peanut oil odor enhances the immunomodulatory effect on immunosuppressed mice by regulating the cAMP signaling pathway via the brain–spleen axis

Author:

Wang Yijin1,Wu Jianfu1,Gong Ying1,Wang Huiting1,Wu Tao1ORCID,Liu Rui1ORCID,Sui Wenjie1,Zhang Min12ORCID

Affiliation:

1. State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science & Technology, Tianjin 300457, China

2. China-Russia Agricultural Processing Joint Laboratory, Tianjin Agricultural University, Tianjin 300392, PR China

Abstract

PL intervention significantly up-regulated the expression levels of cAMP in the brain, with subsequent transfer of cAMP to the spleen which promoted phosphorylation of p65 and IκBα.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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